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Research

Managing your studies and cohorts

Ongoing data collection, site initiations, analysis plans, submission deadlines: one table per study and milestones planned backwards.

Associate prof. (MCU-PH)Full prof. (PU-PH)ArtifactCoworkClaude Project30 min/month

The problem

A closed cohort waiting to be published, another still recruiting, a multicentre study to set up, a risk calculator whose data collection must finish before a conference deadline: each project has its own timeline, partners and regulatory documents.

Step-by-step method

  1. One sheet per study: status (in preparation, site initiation, data collection, closed, under analysis), partners, target and achieved sample size, next visit, regulatory documents.

  2. Milestones planned backwards: late-breaking abstract deadline, end of data collection, database freeze, analysis plan.

  3. A versioned statistical analysis plan (v1.0, v1.1…) and a decision log.

  4. Spin-off projects: for a cohort, list the secondary questions (biomarkers, remodelling, machine learning) and who leads them.

  5. Site initiation: extract the list of documents to provide and the steps, and turn it into a work item.

  6. Prepare meetings (data warehouse, steering committee): Claude drafts the status report from the study sheets.

  7. Link to the database: candidates for a study are identified by querying aggregates, never by exporting identifying data.

  8. Multicentre registries: procedure for sending exams to core laboratories, tracking of quality and of reported missing data.

  9. Assign each study to the right hat: academic, or a service provided to an industry sponsor, depending on who funds it.

Deliverable

A table of studies, milestone alerts, and a status report ready before each meeting.

Safeguards

Regulatory framework for research involving human participants; sensitive data isolated and processed locally; approval by the clinical research department.

Starter prompt

Here are my ongoing studies (short name, status, next deadline). Build a management table with backward-planned milestones for each, and flag those whose data collection will not meet the next submission deadline.

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